Identification of G-quadruplex clusters on human genomic DNA

We identified 9,651 G-quadruplex clusters on human genomic DNA. The paper has been published in Scientific Reports.1 G-quadruplex (G4) is a non-canonical DNA structure that has been found in several regulatory regions, such as telomeres, CpG islands and promoters. The identification of G4-forming sequences is important in elucidating the function of G4 structures on genomic … Continue reading Identification of G-quadruplex clusters on human genomic DNA